Careers
Why Biose Industrie
Founded in 1951, Biose Industrie has has been constantly expanding since 2017 and has increased its workforce five-fold in the last 5 years.
Commitment, Agility, Responsibility and Expertise shape our actions.
We value joint endeavours, accompany individual and collective projects and provide support for professional development.
Offres d'emploi
Organization
Biose Industrie is a drug-GMP certified CDMO for clinical and commercial products. The headquarter founded in France in 1951 focusing on health through the microbiota including product development, clinical and commercial manufacturing of Live Biotherapeutic Product (LBPs). The company has opened a new lab and office space in Woburn, MA focusing on tech transfer and early-stage process and analytical development activities.
Overview
We are seeking a highly motivated candidate to join our growing US team. The candidate will provide valuable support to the process team throughout the fermentation process and will be responsible of conducting the essential analytical tests required such as bacterial counts and contamination detection (in accordance with USP61 and 62 standards), as well as molecular (PCR and PMAqPCR) and physicochemical analyses.
Responsibilities and duties
- Prepare culture media for the fermentation.
- Set up and prepare fermenter cultures up to 5L.
- Monitor fermentations.
- Analyze samples using microbiological, biochemical, or molecular biology techniques.
- Critical interpretation of the results.
- Complete follow-up documents and report activities in the lab notebook.
- Ensure regular reporting to the teams.
Requirements
- An associate or bachelor’s degree in biotechnology, biology, chemistry or related field.
- Proven work experience as a research associate.
- Experience with laboratory equipment and procedures.
- Excellent organizational skills.
- Ability to multitask and manage their time efficiently.
- Ability to work in a team-oriented environment.
Organization
Biose Industrie is a drug-GMP certified CDMO for clinical and commercial products. The headquarter founded in France in 1951 focusing on health through the microbiota including product development, clinical and commercial manufacturing of Live Biotherapeutic Product (LBPs). The company has opened a new lab and office space in Woburn, MA focusing on tech transfer and early-stage process and analytical development activities.
Overview
We are seeking a highly motivated Bioprocess engineer to join our growing US team. The position will be based out of our Woburn laboratory and will require responsibilities ranging from project designing and execution of upstream and downstream processes to data validation and analysis.
The ideal candidate will be highly collaborative and enjoy working in a fast paced environment, while bringing their experience, expertise, and innovative ideas.
Responsibilities and duties
- Design, perform, and oversee execution of upstream (5L bioreactors) and downstream process (centrifugation, tangential flow filtration and freeze-drying) for LBP manufacturing.
- Ensure the implementation and execution of each LBP project according to appropriate client tech transfer requirement and timeline.
- Optimize upstream, downstream and lyophilization processes to increase the yields and ensure reproducibility.
- Conduct bench scale experiments for process optimization, plant support and tech transfer to pilot and manufacturing.
- Ensure that the developed process will be well adapted and scalable to the industrial GMP scale facilities in France.
- Execute associated analytical protocols (numeration, bioburden, molecular biology techniques) as needed.
- Responsible for data analysis and communication.
- Effectively communicate the data, recommendations, and next steps to R&D leadership through scientific meetings, presentations, and documentation.
- Generate standard operating procedures and batch records to document and ensure traceability of the work performed.
- Stay up to date with literature and novel technologies in the related field.
Requirements
- Bachelor’s or Master’s in biomedical, bioprocess, biotechnology engineer or related field.
- A minimum of 2 years of experience as a bioengineer.
- Excellent organizational skills.
- Excellent written and oral communication skills.
- Ability to multitask and manage their time efficiently.
- Ability to work in a team-oriented environment is essential, as the candidate will work closely with other members of the R&D and process development in U.S and France.
Biose industrie est une entreprise pharmaceutique, qui a pour vocation le développement industriel et technologique, la production clinique et commerciale de médicaments microbiotiques – Live Biotherapeutic Products (LBPs).
Biose Industrie, CDMO intégrée, recrute pour son site de production basé à Aurillac (Cantal) un·e : Program Leader F/H
Dans un environnement dynamique et en pleine croissance, intégré·e à l’équipe Business composée de 13 personnes, vous êtes responsable, avec vôtre binôme, du management opérationnel et commercial des programmes clients et des projets internes.
Mission du poste
- Piloter les orientations techniques, scientifiques et industrielles du client
- Piloter toutes les actions transverses contribuant à la réussite du projet
- Animer et coordonner la vie du projet en lien avec les opérationnels, mettre en place et suivre la réalisation du planning
- Organiser et orienter les projets clients de la mise en œuvre des premières expérimentations en R&D jusqu’à la production de lots cliniques
- Assurer le lien et l’interface avec le client
- Valider les investissements liés au projet
- Accompagner les décisions techniques et réglementaires du client
- Garantir le budget et le planning des projets en lien avec les éléments contractuels et les coordinateurs opérationnels de chaque service
- Assurer une veille concurrentielle et les évolutions des besoins clients
Compétences requises
- Pharmacien, PhD ou Bac+5 avec expérience en microbiologie, biotechnologies ou en gestion de projets
- Connaissance de l’environnement pharmaceutique (GMP/FDA)
- Appétence et connaissances de la qualité en industrie pharmaceutique sont un plus
- Capacités de leadership matriciel et de gestion de projets
- Esprit d’équipe pour une collaboration transversale avec les différents services
- Aisance relationnelle, capacités de travail en binôme
- Capacités d’animation de réunions commerciales et opérationnelles
- Maîtrise de l’anglais
Informations supplémentaires
- Type de contrat : CDI